Conopeptides in Addiction Disorders Treatment
نویسندگان
چکیده
Marine cone snails produce venoms (Conotoxins: CT) that have attracted interest as leads in drug design. CT are small peptides containing one or more disulfide bonds. α-CT specifically target different isoforms of nicotinic acetylcholine receptors (nAChR). In view of the important role of nAChR in normal and disease physiology such as addiction disorders, specific targeting of the relevant nAChR subtypes is an attractive pharmaceutical strategy. In this review the potential of α-CT against addiction disorders will be referred and discussed.
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